In a randomized, double-blinded and controlled clinical trial, supplementation with the same pure C15:0 ingredient in fatty15 improved the health outcomes of the Mediterranean diet.
SAN DIEGO, Jan. 18, 2024 /PRNewswire/ -- A game-changing clinical trial has revealed that enhancing the already renowned Mediterranean diet with pure C15:0 supplementation can elevate health outcomes even further.
C15:0 (also called pentadecanoic acid) is the , which was over 90 years ago. have linked higher C15:0 to better metabolic, liver and heart health.
The , published in the American Journal of Clinical Research, has the scientific nutrition community buzzing. Participants were divided into three groups: a caloric-restricted diet, a caloric-restricted diet following Mediterranean diet guidelines, and a caloric-restricted Mediterranean diet with C15:0 supplementation.
The results were astounding––lower weight, less body fat, healthier insulin, glucose, and blood pressure levels. The caloric-restricted Mediterranean diet, both with and without C15:0, resulted in lower body weight as well as lower total cholesterol, triglycerides, and improved liver function compared to just the caloric-restricted group. But the real star? The group supplemented with C15:0 enjoyed the most health benefits––healthiest body weight, lowest liver fat, lower LDL cholesterol, healthier gut microbiome (Bifidobacterium adolescentis), as well as the benefits from pure caloric restriction.
is the world's only pure and science-backed C15:0 supplement. In head-to-head studies, fatty15 had 36+ clinically relevant cellular benefits, which was (EPA). Even among leading longevity-enhancing molecules, .
, the Mediterranean diet is a heart-health champion associated with . Vegetables, fruit, moderate alcohol consumption, fish, shellfish, whole grains, legumes, nuts, and high monounsaturated fats – these .
Yet, amidst the diet and nutritional revolution, could be contributing to the surge in type 2 diabetes, heart disease, and nonalcoholic fatty liver disease (NAFLD).
Dr. Stephanie Venn-Watson, co-founder of Seraphina Therapeutics, emphasizes, "This recent clinical trial underscores C15:0 as a critical, essential nutrient for our long-term health. It's becoming increasingly urgent to understand how C15:0 deficiencies are impacting global health, and more importantly, how we can replenish C15:0 levels to help restore both individual and global health."
Read the study
Chooi et al. . The American Journal of Clinical Nutrition (2023): In Press.
About Seraphina Therapeutics. Inc.
Seraphina Therapeutics, Inc. is a health and wellness company dedicated to advancing global health through the discovery of essential fatty acids and micronutrient therapeutics. Through rigorous breakthrough science, the company develops fatty acid supplements, food fortifiers, and nutritional interventions to strengthen cells, keep mitochondria working and advance cellular homeostasis to counter age-related breakdown. With its team of industry-leading scientists, Seraphina Therapeutics challenges long-held approaches to nutrition, enabling the creation of novel health products designed to support quality of life. For more information, please visit and .
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